He is the main host of radio and television program Ang Dating Daan (English: The Old Path, Portuguese: O Caminho Antigo, Spanish: El Camino Antiguo), considered as the longest-running religious program in the Philippines.
Soriano is known for his signature method of "Bible Expositions".
He also had numerous religious debates with different pastors.
An incident when he used a defamatory word in his television show On April 7, 1964, three days after his 17th birthday, Eliseo was baptised in Seneguelasan, Bacoor, Cavite, and became an official member of the Iglesia ng Dios kay Kristo Hesus, Haligi at Suhay ng Katotohanan (Church of God in Christ Jesus, Pillar and Support of the Truth in English) founded by Nicolas Perez where his parents were also members.
("Members of the Church of God in Christ Jesus, Pillar and Ground of Truth, Philippines, Inc." in English).
Because of the similarity between the name used by Gugulan's group and Soriano's group, the former filed a suit, which was resolved by the Supreme Court of the Philippines in 2001 in favor of Gugulan's group and Soriano's group was ordered to change their church's name.
In 1976, Soriano and his allies left Gugulan's sect.
Bulandres (New Apostolic Church member) and Roejen M.
He is currently on exile due to the various death threats he received during his controversial years and his countless libel cases he faces in the Philippines, from the people he defamed.
He used this opportunity to preach in other countries.
In 1969, Nicolas Antiporda Perez, who was then the church's presiding minister, bestowed upon Soriano the title minister making him the only minister in the Iglesia ng Dios kay Kristo Hesus, Haligi at Suhay ng Katotohanan at that time.
Rumors were circulating that Soriano is going to be Perez's successor.
Currently, Ang Dating Daan airs in 73 countries worldwide including United States, Brazil, Uruguay, Portugal (as "O Caminho Antigo"), Spain (as "El Camino Antiguo"), India, South Africa, Saipan.